show all | hide all No of entries

Information on EC 2.1.1.203 - tRNA (cytosine34-C5)-methyltransferase

for references in articles please use BRENDA:EC2.1.1.203
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.203 tRNA (cytosine34-C5)-methyltransferase
IUBMB Comments
The human enzyme is specific for C5-methylation of cytosine34 in tRNA precursors. The intron in the human pre-tRNALeu(CAA) is indispensable for the C5-methylation of cytosine in the first position of the anticodon. It is not able to form 5-methylcytosine at positions 48 and 49 of human and yeast tRNA precursors .
Specify your search results
Select one or more organisms in this record:
Word Map
The enzyme appears in viruses and cellular organisms
Reaction Schemes
Synonyms
nop2/sun domain family member 2, htrm4, cytosine-5 rna methyltransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + cytosine34 in tRNA precursor = S-adenosyl-L-homocysteine + 5-methylcytosine34 in tRNA precursor
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
Select items on the left to see more content.