EC Number   |
Natural Substrates |
|---|
   5.6.2.2 | ATP + H2O |
- |
| 5.6.2.2 | DNA + ATP + H2O |
- |
| 5.6.2.2 | DNA + ATP + H2O |
cleavage, relaxation, decatenation, and religation of DNA |
| 5.6.2.2 | DNA + ATP + H2O |
reverse gyrase is a DNA topoisomerase endowed with ATP-dependent positive supercoiling activity. It is typical of microorganisms living at high temperature and might play a role in maintenance of genome stability and repair |
| 5.6.2.2 | DNA + ATP + H2O |
the enzyme helps disentangle chromosomes to facilitate cell division |
| 5.6.2.2 | double-stranded DNA + ATP + H2O |
the enzyme generates ATP-dependent double-strand breaks with two-nucleotide overhangs on supercoiled or linear DNA. topoVI is covalently attached to the 5'-ends of the broken DNA |
| 5.6.2.2 | dsDNA + ATP + H2O |
breakage, passage, decatenation, and rejoining of dsDNA |
| 5.6.2.2 | dsDNA + ATP + H2O |
breakage, passage, decatenation, and rejoining of dsDNA, enzyme is required for conrol of DNA topology |
| 5.6.2.2 | dsDNA + ATP + H2O |
breakage, passage, decatenation, and rejoining of dsDNA, enzyme is required for control of DNA topology |
| 5.6.2.2 | more |
- |
