EC Number   |
Natural Substrates |
|---|
    5.1.99.4 | (2S)-2-methylacyl-CoA |
- |
| 5.1.99.4 | (2S)-2-methylacyl-CoA |
natural substrates are branched chain alpha-methylacyl coenzyme A esters |
| 5.1.99.4 | (2S)-2-methylacyl-CoA |
the enzyme plays an important role in peroxisomal beta-oxidation of branched-chain fatty acids from red meat and dairy products, the enzyme is a biomarker overexpressed in prostate carcinomas and is associated with prostate cancer progression |
| 5.1.99.4 | more |
enzyme expression is increased in extramammary Paget disease, EMPD, overview |
| 5.1.99.4 | more |
the enzyme can distinguish hepatocellular carcinoma and dysplastic hepatocytes from benign nondysplastic hepatocytes, overview |
| 5.1.99.4 | more |
the enzyme is essential for the beta-oxidation of bile acid intermediates and branched-chain fatty acids |
| 5.1.99.4 | more |
the enzyme is involved in gastrointestinal malgnancies |
| 5.1.99.4 | more |
the enzyme is involved in metabolism of branched-chain fatty acids, expression of AMACR in colorectal carcinoma is correlated with tumor differentiation, overview |
| 5.1.99.4 | more |
the enzyme prepares branched chain fatty acids to be metabolized for energy and is implicated in the activation of the COX-inhibiting form of ibuprofen |
| 5.1.99.4 | more |
the risk of familial, but not sporadic, prostate cancer may be associated with germline variation in the AMACR gene, overview |
