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Information on EC 5.1.99.4 - alpha-methylacyl-CoA racemase

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EC Tree
     5 Isomerases
         5.1 Racemases and epimerases
             5.1.99 Acting on other compounds
                5.1.99.4 alpha-methylacyl-CoA racemase
IUBMB Comments
alpha-methyl-branched acyl-CoA derivatives with chain lengths of more than C10 are substrates. Also active towards some aromatic compounds (e.g. ibuprofen) and bile acid intermediates, such as trihydroxycoprostanoyl-CoA. Not active towards free acids
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Word Map
  • 5.1.99.4
  • prostate
  • adenocarcinoma
  • cytokeratins
  • papillary
  • needle
  • high-grade
  • neoplasia
  • prostatectomy
  • gleason
  • intraepithelial
  • vimentin
  • prostate-specific
  • acinar
  • urothelial
  • pathologist
  • 34betae12
  • beta-oxidation
  • hgpin
  • suspicious
  • transurethral
  • immunophenotype
  • oncocytic
  • phytanic
  • nephrogenic
  • chromophobe
  • oncocytomas
  • nucleoli
  • pristanic
  • atypia
  • metanephric
  • chrcc
  • drug development
  • pharmacology
  • tubulocystic
  • tmprss2-erg
  • sarcomatoid
  • hobnail
  • diagnostics
  • medicine
  • immunomarkers
  • fuhrman
  • immunoprofile
  • adenosis
  • cribriform
  • tubulopapillary
  • analysis
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
amacr, p504s, alpha-methylacyl-coenzyme a racemase, alpha-methylacyl coenzyme a racemase, alpha-methylacyl coa racemase, amacr/p504s, 2-methylacyl-coa racemase, alpha-methyl coa racemase, 2-arylpropionyl-coa epimerase, amacr 1a, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(2S)-2-methylacyl-CoA = (2R)-2-methylacyl-CoA
show the reaction diagram
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