EC Number |
Natural Substrates |
---|
2.4.1.198 | more |
- |
2.4.1.198 | more |
enzyme is active in a complex of at least 4 proteins, termed GPI1, PIG-A, PIG-C and PIG-H, in which GPI1 is absolutely essential for stabilization |
2.4.1.198 | more |
enzyme is active in a complex of at least 5 proteins, termed GPI1, PIG-P, PIG-A, PIG-C and PIG-H, PIG-P is absolutely required |
2.4.1.198 | more |
enzyme defect in paroxysmal nocturnal hemoglobinuria |
2.4.1.198 | more |
enzyme exists as a complex of at least 3 proteins PIG-A or GPI3, PIG-C or GPI2 and GPI1, in which PIG-A, not PIG-C, is the substrate binding component |
2.4.1.198 | more |
biosynthetic pathway and subcellular localization, overview |
2.4.1.198 | more |
glycosylphosphatidylinositol anchoring is essential for transport of cell surface proteins and enzyme deficieny leads to defective cell wall synthesis and cell death |
2.4.1.198 | UDP-N-acetyl-alpha-D-glucosamine + 1-phosphatidyl-1D-myo-inositol |
- |
2.4.1.198 | UDP-N-acetyl-D-glucosamine + 1-phosphatidyl-1D-myo-inositol |
- |
2.4.1.198 | UDP-N-acetyl-D-glucosamine + phosphatidylinositol |
- |