EC Number |
Natural Substrates |
---|
2.3.1.250 | (9Z)-hexadec-9-enoyl-CoA + [Wnt1]-L-serine |
- |
2.3.1.250 | (9Z)-hexadec-9-enoyl-CoA + [Wnt3a]-L-serine |
- |
2.3.1.250 | (9Z)-hexadec-9-enoyl-CoA + [Wnt3]-L-serine |
- |
2.3.1.250 | (9Z)-hexadec-9-enoyl-CoA + [Wnt5a]-L-serine |
- |
2.3.1.250 | (9Z)-hexadec-9-enoyl-CoA + [Wnt5]-L-serine |
- |
2.3.1.250 | (9Z)-hexadec-9-enoyl-CoA + [Wnt]-L-serine |
- |
2.3.1.250 | more |
enzyme Porc functions on the N-terminal 24-amino acid domain (83-106) of Wg, binding of Porc with Wg is essential for its activity |
2.3.1.250 | more |
PORCN splice variants differ globally in signaling activity |
2.3.1.250 | (9Z)-hexadec-9-enoyl-CoA + [Wnt]-L-serine |
the enzyme catalyzes posttranslational modification of Wnts with palmitoleic acid. PORCN is necessary and sufficient for Wnt acylation. PORCN intimately recognizes the local structure of Wnt around the site of acylation |
2.3.1.250 | (9Z)-hexadec-9-enoyl-CoA + [Wnt3a]-L-serine |
the enzyme catalyzes the palmitoylation of Ser209 and Cys77 of Wnt3a |