EC Number |
Natural Substrates |
---|
1.1.1.283 | (S)-lactaldehyde + NADP+ |
- |
1.1.1.283 | isovaleraldehyde + NADPH + H+ |
catalytic mechanism involving Ser127, Tyr165, and Lys169, overview. The carbonyl oxygen interactswith the side chain of Ser127, Tyr165 through hydrogen bonds (about 2.7 A), giving a distance of 3.0 A between the C4 atom of the nicotinamide and the carbonyl carbon of substrate |
1.1.1.283 | methylglyoxal + NADH + H+ |
- |
1.1.1.283 | methylglyoxal + NADPH |
- |
1.1.1.283 | methylglyoxal + NADPH |
similar enzyme with NADPH requirement |
1.1.1.283 | methylglyoxal + NADPH |
similar enzyme with NADPH requirement, no reaction with NAD+, NADH and NADP+ |
1.1.1.283 | methylglyoxal + NADPH + H+ |
- |
1.1.1.283 | more |
important role in the suppression of filamentation in response to isoamyl alcohol |