EC Number |
Natural Substrates |
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1.1.1.206 | more |
the bifunctional enzyme of Cochlearia officinalis is not stereospecific, in contrast to the Solanaceae species, and catalyzes both tropinone reductase reactions, a tyrosine residue in the active site of Cochlearia officinalis TR is responsible for binding and orientation of tropinone, overview |
1.1.1.206 | more |
the enzyme TR-I has a wide substrate specificity but does not cover the substrates of other well-known plant SDR related to menthol metabolism |
1.1.1.206 | more |
tropinone feeding experiments |
1.1.1.206 | tropine + NADP+ |
last step in biosynthesis of tropine |
1.1.1.206 | tropine + NADP+ |
role in the pathway for tropine catabolism |
1.1.1.206 | tropine + NADP+ |
- |
1.1.1.206 | tropinone + NADPH + H+ |
tropinone reductase II |
1.1.1.206 | tropinone + NADPH + H+ |
- |
1.1.1.206 | tropinone + NADPH + H+ |
preferred substrate |
1.1.1.206 | tropinone + NADPH + H+ |
tropine is the precursor of the tropane alkaloids hyoscyamine and scopolamine |