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EC Number
Natural Substrates
Commentary (Nat. Sub.)
2.7.11.25
ATP + ERK5
substrate of MEKK2 and MEKK3, activation of the ERK-dependent signaling pathway
2.7.11.25
ATP + GLI1
mitogen-activated kinase kinase kinase 1 phosphorylates the C-terminal region of GLI1
2.7.11.25
ATP + IKKalpha
-
2.7.11.25
ATP + JNK
i.e. Jun amino terminal kinase
2.7.11.25
ATP + JNK1
-
2.7.11.25
ATP + JNK2
-
2.7.11.25
ATP + MAPKK
MAPKK activation
2.7.11.25
ATP + MEK
-
2.7.11.25
ATP + MEK
PI3K/PKC/Raf-1-independent activation of the MEK/ERK signaling pathway
2.7.11.25
ATP + Mek1
activation
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