EC Number   |
Metals/Ions |
Reference |
|---|
   1.13.11.50 | Fe2+ |
0.9-1.0 iron atoms per subunit, bound to active enzyme, essential for catalytic activity |
636327 |
| 1.13.11.50 | Fe2+ |
active site nonheme monoiron(II) center, facially ligated by three histidine residues, overview. Spectral analysis of Dke1 FeII-alpha-keto acid complexes with 4-hydroxyphneylpyruvate, overview |
725198 |
| 1.13.11.50 | Iron |
an interplay of residues Glu98, His104, Glu11 (from the neighbor subunit), and Arg80 is the most important for the Fe2+ transport in and out of the protein. The Fe2+ ion when expelled from the binding site can be trapped at different locations within the enzyme. The neighborhood of residue Glu11 (form the neighbor subunit) is the second most favorable binding site for the Fe2+ ion after the active site |
742322 |
| 1.13.11.50 | Fe3+ |
citrate, no interference with Fe2+ |
696107 |
| 1.13.11.50 | Ni2+ |
dependent on |
764544 |
| 1.13.11.50 | Iron |
dependent on, metalloenzyme, 1 iron bound per subunit, required for positioning of the substrate and for rendering of the appropriate electronic environment |
657866 |
| 1.13.11.50 | Fe2+ |
Dke1 contains an atypical, three-histidine-ligated, mononuclear non-heme Fe2+ center, spectroscopic analysis, overview. Stabilizing effect of Glu98 on the 6C geometry of the metal center, priming it for substrate ligation. Also Thr107 stabilizes the Fe(II) cofactor |
711267 |
| 1.13.11.50 | Fe2+ |
essential for activity |
671683 |
| 1.13.11.50 | Fe2+ |
Fe2+-dependent enzyme, 1 molecule per subunit |
675466 |
| 1.13.11.50 | Fe2+ |
its active site consists of a redox-active iron(II) center |
764545 |
