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EC Number
Localization
Commentary
GeneOntology No.
Reference
3.4.22.49
centrosome
-
GO:0005813
AmiGO
QuickGO
731689
,
732669
,
732703
3.4.22.49
centrosome
localized in centrosomes before anaphase
GO:0005813
AmiGO
QuickGO
638869
3.4.22.49
chromosome
-
GO:0005694
AmiGO
QuickGO
697240
,
731697
3.4.22.49
chromosome
the spatial localization of separase varies with the progression of the cell cycle. In interphase cells, separase is localized in the cytoplasm, but during mitosis it accumulates in the nucleus and associates with chromosomes
GO:0005694
AmiGO
QuickGO
752903
3.4.22.49
cytoplasm
Cut1 seems to be localized in the cytoplasm
GO:0005737
AmiGO
QuickGO
638856
3.4.22.49
cytoplasm
in nondividing cells in healthy tissue, immunofluorescence microscopy
GO:0005737
AmiGO
QuickGO
697382
3.4.22.49
cytoplasm
prodominant localisation
GO:0005737
AmiGO
QuickGO
700280
3.4.22.49
cytoplasm
separase is abundantly expressed within the cytoplasm of a broad range of human tumor cell lines, including MDA-MB-231 breast carcinoma cells
GO:0005737
AmiGO
QuickGO
718433
3.4.22.49
cytoplasm
the spatial localization of separase varies with the progression of the cell cycle. In interphase cells, separase is localized in the cytoplasm, but during mitosis it accumulates in the nucleus and associates with chromosomes
GO:0005737
AmiGO
QuickGO
752903
3.4.22.49
membrane
-
GO:0016020
AmiGO
QuickGO
718433
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