EC Number |
Inhibitors |
Structure |
---|
7.1.2.2 | 1,3-dicyclohexyl carbodiimide |
- |
|
7.1.2.2 | 2-hydroxyglutarate |
- |
|
7.1.2.2 | 2-oxoglutarate |
- |
|
7.1.2.2 | 2-[[4-(trifluoromethoxy)phenyl]hydrazinylidene]propanedinitrile |
acts as an uncoupler and abolishes ATP synthesis |
|
7.1.2.2 | 42-58 IF1 synthetic peptide |
inhibits both H+ uptake and H+ release of the enzyme complex |
|
7.1.2.2 | 7-chloro-4-nitrobenz-2-oxa-1,3-diazole |
i.e. NBD-Cl, MgADP at low concentrations promotes the inhibition, whereas at higher concentrations EcF1 is protected from inhibition, that need to be higher for the mutant betaY331W, than for the wild-type enzyme. In absence of added MgATP, selenite slows down inhibition of EcF1 by 0.2 mM NBD-Cl |
|
7.1.2.2 | 7-Chloro-4-nitrobenzo-2-oxa-1,3-diazole |
- |
|
7.1.2.2 | adenosine-5'-(beta,gamma-imino)-triphosphate |
inhibits F1 rotation |
|
7.1.2.2 | ADP |
- |
|
7.1.2.2 | ADP |
negative allosteric effector |
|