EC Number |
Inhibitors |
Structure |
---|
6.2.1.B11 | acetyl phosphate |
- |
|
6.2.1.B11 | AMP |
slight inhibition |
|
6.2.1.B11 | ATP |
ATP inhibits the acetate-forming direction of the reaction, with 50% inhibitory concentration of 0.81 mM, which is in the range of its physiological concentration. Diphosphate displays mixed inhibition versus each of the three substrates, acetyl-CoA, ADP, and phosphate. No inhibition by lactate and pyruvate |
|
6.2.1.B11 | cAMP |
- |
|
6.2.1.B11 | D-fructose 1,6-bisphosphate |
- |
|
6.2.1.B11 | D-fructose 6-phosphate |
- |
|
6.2.1.B11 | D-glucose 6-phosphate |
- |
|
6.2.1.B11 | diphosphate |
diphosphate inhibits the acetate-forming direction of the reaction, with 50% inhibitory concentration of 0.75 mM, which is in the range of its physiological concentration. ATP displays mixed inhibition versus each of the three substrates, acetyl-CoA, ADP, and phosphate |
|
6.2.1.B11 | glyoxylate |
inhibits the activity in the acetate-forming direction |
|
6.2.1.B11 | NAD+ |
- |
|