EC Number   |
Inhibitors |
Structure  |
|---|
   3.4.22.41 | more |
downregulation of cathepsin F mRNA by E-64d; treatment with retinol/palmitic acid increases mRNA-level of cystatin B coupled with decrease in cathepsin F activity; treatment with retinol/palmitic acid increases mRNA-level of cystatin C coupled with decrease in cathepsin F activity |
 |
| 3.4.22.41 | more |
not inhibited by pepstatin A |
|
| 3.4.22.41 | more |
the prodomain effectively inhibits the enzyme in which the ERFNAQ motif plays a critical role in the inhibition, but the GTFD motif is also required for complete inhibition |
|
| 3.4.22.41 | Zn2+ |
5.94% residual activity at 1 mM |
  |
| 3.4.22.41 | Cu2+ |
11.6% residual activity at 5 mM |
|
| 3.4.22.41 | EDTA |
6.52% inhibition at 0.1 mM |
|
| 3.4.22.41 | Co2+ |
6.85% residual activity at 5 mM |
|
| 3.4.22.41 | Hg2+ |
0.81% residual activity at 5 mM |
|
| 3.4.22.41 | 1,10-phenanthroline |
15.28% inhibition at 0.1 mM |
|
| 3.4.22.41 | NEM |
44.59% inhibition at 0.1 mM |
|
