EC Number |
Inhibitors |
Structure |
---|
1.3.1.10 | (E)-N-(1,2-dimethyl-1H-indol-3-ylmethyl)-N-methyl-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide |
- |
|
1.3.1.10 | 5-chloro-2-phenoxyphenol |
- |
|
1.3.1.10 | 5-ethyl-2-phenoxyphenol |
- |
|
1.3.1.10 | 6-methyl-2-(propane-1-sulfonyl)-4a,7a-dihydro-2H-thieno[3,2-d][1,2,3]diazaborinin-1-ol |
diazaborine derivative 2b18, binds only in presence of NADH or NADPH, non-competitive inhibition, 0.2 mM lead to 25% inhibition, 0.52 mM to 50%, 1.56 mM to 80%. Increasing the inhibitor concentrations lead to preference for shorter acyl chain lengths |
|
1.3.1.10 | AFN-1252 |
- |
|
1.3.1.10 | aquastatin A |
a natural inhibitor from the fungus Sporothrix sp. strain FN611, mixed-type inhibition against FabI with respect to the substrate trans-2-octenoyl N-acetylcysteamine and NADPH, prevents the growth of Staphylococcus aureus and methicillin-resistant Staphylococcus aureus with minimum inhibitory concentration of 0.016-0.032 mg/ml, overview |
|
1.3.1.10 | degalactosylated aquastatin A |
a natural inhibitor from the fungus Sporothrix sp. strain FN611 |
|
1.3.1.10 | Hexachlorophene |
half-maximal inhibition at 0.004 mM |
|
1.3.1.10 | iodoacetate |
- |
|
1.3.1.10 | more |
not inhibited by: triclosan |
|