EC Number   |
Activating Compound |
Reference |
|---|
    4.1.1.32 | 2-mercaptoethanol |
maximum stimulation at 75 mM |
652113 |
| 4.1.1.32 | dithiothreitol |
maximum at 10-40 mM, 30% stimulation |
652113 |
| 4.1.1.32 | Ferroactivator |
ferroactivator + Fe2+, stimulates both directions of the reaction |
4356 |
| 4.1.1.32 | ITP |
stimulates Mn2+-dependent CO2-oxaloacetate exchange |
4344 |
| 4.1.1.32 | Mn2+ |
activity regulator, 0.7 mM leads to full enzyme stimulation |
678421 |
| 4.1.1.32 | more |
all-trans-retinoic acid is a transcriptional inducer of the PEPCK-C gene. 9-cis-retinoic acid and all-trans-retinoic acid stimulate PEPCK-C expression in 3T3-442A adipocytes |
693786 |
| 4.1.1.32 | more |
ketogenic diet-fed rats have increased fat mass and phosphoenolpyruvate carboxykinase activity |
694251 |
| 4.1.1.32 | more |
methylprednisolone induces enzyme expressions via cAMP |
669990 |
| 4.1.1.32 | more |
PEPCK mRNA expression in the subcutaneous adipose tissues is associated with body mass index and plasma triacylglycerol and total cholesterol levels, but is not correlated with insulin resistance index |
693990 |
| 4.1.1.32 | more |
PEPCK mRNA is elevated in cells cultured at high density, expression is induced by contact inhibition in the presence of serum, at low culture density, dexamethasone induces PEPCK mRNA 5-8fold, at high culture density 2-3fold |
649586 |
