EC Number   |
Activating Compound |
Reference  |
|---|
   3.4.24.19 | Enhancer glycoprotein |
bound to the carboxyl propeptide of type I procollagen |
31034 |
| 3.4.24.19 | Enhancer glycoprotein |
enhances activity of C-proteinase |
31034, 31036 |
| 3.4.24.19 | Enhancer glycoprotein |
characterization |
31043 |
| 3.4.24.19 | Enhancer glycoprotein |
enhancer may play a regulatory role in procollagen processing |
31043 |
| 3.4.24.19 | Enhancer glycoprotein |
stimulates activity |
668838 |
| 3.4.24.19 | TGFbeta |
increases the expression of BMP-1 and Tld in human dermal fibroblasts |
668838 |
| 3.4.24.19 | PCPE-1 |
enhances degredation of procollagen type I 5 fold, enhances C-terminal processing of procollagen type III when this substrate is in its native, disulfide-bonded conformation, has no effect on the in vitro BMP-1 processing of procollagen VII, procollagen V N-propeptide, laminin 5 gamma2 chain, osteoglycin, prolysyl oxidase or chordin |
669352 |
| 3.4.24.19 | procollagen C-proteinase enhancer 1 |
enhances full length BMP1 and not truncated versions missing the most COOH-terminal EGF and CUB domains |
687503 |
| 3.4.24.19 | Frizzled-related protein |
secreted Frizzled-related protein sFRP2 serves as a direct enhancer of procollagen C proteinase activity of tolloid-like metalloproteinases. The level of fibrosis, in which procollagen processing by tolloid-like proteinases has a rate-limiting role, is markedly reduced in Sfrp2-null mice subjected to myocardial infarction. This reduced level of fibrosis is accompanied by significantly improved cardiac function |
700348 |
| 3.4.24.19 | procollagen C-proteinase enhancer 1 |
procollagen C-proteinase enhancer 1 specifically stimulates the PCP activity of bone morphogenic protein 1 |
711771 |
