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Literature summary for 3.4.24.19 extracted from

  • Moali, C.; Font, B.; Ruggiero, F.; Eichenberger, D.; Rousselle, P.; Francois, V.; Oldberg, A.; Bruckner-Tuderman, L.; Hulmes, D.J.
    Substrate-specific modulation of a multisubstrate proteinase. C-terminal processing of fibrillar procollagens is the only BMP-1-dependent activity to be enhanced by PCPE-1 (2005), J. Biol. Chem., 280, 24188-24194.
    View publication on PubMed
Search for more literature for 3.4.24.19

Activating Compound

Activating Compound Comment Organism Structure
PCPE-1 enhances degredation of procollagen type I 5 fold, enhances C-terminal processing of procollagen type III when this substrate is in its native, disulfide-bonded conformation, has no effect on the in vitro BMP-1 processing of procollagen VII, procollagen V N-propeptide, laminin 5 gamma2 chain, osteoglycin, prolysyl oxidase or chordin Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
expression in 293-EBNA cells Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
to homogeneity by affinity chromatography Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Procollagen type I + H2O
-
 Homo sapiens Type I pNcollagen + C-propeptides
-
 ?
procollagen type III + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
BMP-1
-
 Homo sapiens
bone morphogenetic protein 1/tolloid
-
 Homo sapiens
PCP
-
 Homo sapiens
PCP-1
-
 Homo sapiens
Procollagen C-proteinase
-
 Homo sapiens
TId
-
 Homo sapiens
tolloid
-
 Homo sapiens

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.0056 0.0083 Procollagen type I
-
 Homo sapiens