EC Number   |
Activating Compound |
Reference |
|---|
   1.1.1.244 | activator protein ACT |
UniProt ID I3EA59, the in vitro activity of Bacillus methanolicus Mdh is increased by the endogenous activator protein Act, a Nudix hydrolase, in a pH-dependent manner. Act increases the Vmax of the enzyme and decreases the Km for methanol, the increase is 20fold at pH 7.4 and 9fold at pH 9.0 |
742514 |
| 1.1.1.244 | more |
Mdh2 from Cupriavidus necator does not require activation by and is insensitive to known activators such as Bacillus methanolicus ACT and Escherichia coli Nudix hydrolase NudF, or putative native Cupriavidus necator activators in the Nudix family under mesophilic condition. The enzyme exhibits higher or comparable activity and affinity toward methanol relative to the Bacillus methanolicus Mdh with or without activator ACT in a wide range of temperatures |
741715 |
| 1.1.1.244 | more |
no activation by activator protein Act, UniProt ID I3EA59 |
743223 |
| 1.1.1.244 | more |
strongly stimulated by the ACT protein |
656074, 656101 |
| 1.1.1.244 | more |
the enzyme is activated by several Nudix hydrolases, relative activities of Adh enzymes, overview |
742514 |
| 1.1.1.244 | NudBC |
a Nudix hydrolase from Bacillus coagulans, UniProt ID G2TKZ3 |
742514 |
| 1.1.1.244 | NudDK |
a Nudix hydrolase from Desulfotomaculum kuznetsovii, UniProt ID F6CJI1 |
742514 |
| 1.1.1.244 | NudF protein |
can be catalytically stimulated by the Bacillus subtilis NudF protein in vitro |
726329 |
| 1.1.1.244 | NudLF |
a Nudix hydrolase from Lysinibacillus fusiformis, UniProt ID D7WXY3 |
742514 |
| 1.1.1.244 | NudLS |
a Nudix hydrolase from Lysinibacillus sphaericus, UniProt ID B1HRL7 |
742514 |
