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Version 2014-12-22
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Details for ventral disc
Gene ontology ID
GO:0097597
Definition
Specialized organelle found in Giardia species (trophozoite stage) and characterized by a spiral array of microtubules and microtubule-associated structures including dorsal microribbons and crossbridges. The edge of the ventral disc narrows into a lateral crest. The ventral disk mediates mechanical attachment of the trophozoite to the host's intestinal wall, and contains the contractile proteins actinin, alpha-actinin, myosin, and tropomyosin working towards contraction of the disk involved in adherence
Comment
Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.
Synonyms
1. adhesive disc
2. ventral adhesive disc
3. ventral disk
References
1. GOC: giardia
2. ISBN 9780124260207
3. PMID 11432808
4. PMID 4777416
5. PMID 5961344
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