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Gene ontology
Version 2014-12-22
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Details for LUBAC complex
Gene ontology ID
GO:0071797
Definition
A ubiquitin ligase complex that catalyzes linear head-to-tail polyubiquitin conjugation on its targets. In human the complex consists of RBCK1, RNF31 and SHARPIN, and has an MW of approximately 600 kDa, suggesting a heteromultimeric assembly of its subunits. LUBAC stands for Linear Ubiquitin Chain Assembly Complex
References
1. GOC: sp
2. PMID 17006537
3. PMID 19136968
4. PMID 21455180
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