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Version 2014-12-22
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Details for nuclear pore outer ring
Gene ontology ID
GO:0031080
Definition
A subcomplex of the nuclear pore complex (NPC) that forms the outer rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two outer rings each contain multiple copies of the following proteins: Nup133p, Nup120p, Nup145Cp, Nup85p, Nup84p, Seh1p, and Sec13p. In vertebrates, the two outer rings each contain multiple copies of the following proteins: Nup133, Nup160, Nup96, Nup75, Nup107, Seh1, Sec13, Nup43, Nup37, and ALADIN. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referred to as the Nup84 complex (S. cerevisiae) or the Nup107-160 complex (vertebrates)
Synonyms
1. Nup107-120 complex
2. Nup107-160 complex
3. Nup84 complex
References
1. GOC: dgf
2. PMID 18046406
3. PMID 19524430
4. PMID 20947011
5. PMID 22419078
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