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Gene ontology
Version 2014-12-22
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Details for endodeoxyribonuclease activity
Gene ontology ID
GO:0004520
Definition
Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks
Synonyms
1. DNA nicking activity
2. endonuclease G activity
References
1. GOC: mah
2. ISBN 0198547684
3. Reactome: R-HSA-110359 "APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site"
4. Reactome: R-HSA-5686440 "MUS81:EME1,EME2 cleaves D-loop"
5. Reactome: R-HSA-5686657 "ERCC1:XPF cleaves flaps generated by SSA"
6. Reactome: R-HSA-5687464 "MRN and RBBP8 resect DNA DSBs in MMEJ"
7. Reactome: R-HSA-5690988 "3'-incision of DNA by ERCC5 (XPG) in GG-NER"
8. Reactome: R-HSA-5693584 "Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2)"
9. Reactome: R-HSA-5693608 "Initial resection of double-strand break ends"
10. Reactome: R-HSA-6782204 "5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER"
11. Reactome: R-HSA-6782224 "3' incision by ERCC5 (XPG) in TC-NER"
12. Reactome: R-HSA-9023941 "MRN:CtIP endonucleolytically cleaves single-strand DNA 3' to SPO11"
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