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Gene ontology
Version 2014-12-22
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Details for phosphoribosylformylglycinamidine cyclo-ligase activity
6.3.3.1
Gene ontology ID
GO:0004641
Definition
Catalysis of the reaction: 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + ATP = 5-amino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H(+) + phosphate
Synonyms
1. 2-(formamido)-1-N-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming)
2. 2-(formamido)-N1-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming)
3. 5'-aminoimidazole ribonucleotide synthetase activity
4. AIR synthase activity
5. AIR synthetase activity
6. AIRS activity
7. phosphoribosyl-aminoimidazole synthetase activity
8. phosphoribosylaminoimidazole synthetase activity
References
1. EC 6.3.3.1
2. RHEA: 23032
3. KEGG REACTION: R04208
4. MetaCyc AIRS-RXN
5. Reactome: R-HSA-73810 "FGAM + ATP => AIR + ADP + Pi"
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