6.3.5.2Gene ontology ID
GO:0003922
Definition
Catalysis of the reaction: ATP + XMP + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate + 2H(+)
Synonyms
1. glutamine amidotransferase activity
2. GMP synthase (glutamine-hydrolysing)
3. GMP synthetase (glutamine-hydrolysing)
4. GMP synthetase (glutamine-hydrolyzing) activity
5. guanosine 5'-monophosphate synthetase activity
6. guanosine monophosphate synthetase (glutamine-hydrolyzing)
7. guanylate synthetase (glutamine-hydrolyzing)
8. xanthosine 5'-phosphate amidotransferase activity
9. xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming)
References
1. RHEA: 11680
2. EC 6.3.5.23. MetaCyc GMP-SYN-GLUT-RXN4. Reactome: R-HSA-73792 "XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate"
5. Wikipedia: GMP synthase (glutamine-hydrolysing)
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is a part of the parent element
is related to the parent element
derives from the parent element
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at least 1 tissue/ enzyme/ localization link in this branch
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tissue/ enzyme/ localization link to BRENDA