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Gene ontology
Version 2014-12-22
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Details for fatty acid synthase activity
2.3.1.85
Gene ontology ID
GO:0004312
Definition
Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = long-chain fatty acid + n+1 CoA + n CO2 + 2n NADP+
Synonyms
1. acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing)
2. fatty-acid synthase activity
References
1. EC 2.3.1.85
2. MetaCyc FATTY-ACID-SYNTHASE-RXN
3. Reactome: R-HSA-75872 "acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O"
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