1.3.1.2Gene ontology ID
GO:0017113
Definition
Catalysis of the reaction: 5,6-dihydrouracil + NADP+ = uracil + NADPH + H+
Synonyms
1. 4,5-dihydrothymine: oxidoreductase activity
2. 5,6-dihydrouracil:NADP+ 5-oxidoreductase activity
3. dehydrogenase, dihydrouracil (nicotinamide adenine dinucleotide phosphate)
4. DHPDH
5. DHU dehydrogenase activity
6. dihydropyrimidine dehydrogenase activity
7. dihydrothymine dehydrogenase activity
8. dihydrouracil dehydrogenase (NADP)
9. dihydrouracil dehydrogenase (NADP+) activity
10. DPD
11. hydropyrimidine dehydrogenase activity
References
1. EC 1.3.1.22. MetaCyc 1.3.1.2-RXN3. Reactome: R-HSA-73585 "uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+"
4. Reactome: R-HSA-73616 "thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+"
5. RHEA: 18093
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