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Ontology explorer

Gene ontology
Version 2014-12-22
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Details for RNA NAD-cap (NAD-forming) hydrolase activity
Gene ontology ID
GO:0110152
Definition
Catalysis of the reaction: a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + H(+) + NAD(+)
Comment
This reaction specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
References
1. GOC: sp
2. PMID 28283058
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