immunological synapseGene ontology ID
GO:0001772
Definition
An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction
Synonyms
1. c-SMAC
2. supramolecular activation cluster
References
1. GOC: mgi curators
2. PMID 112440413. PMID 113763004. Wikipedia: Immunological synapse
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derives from the parent element
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at least 1 tissue/ enzyme/ localization link in this branch
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tissue/ enzyme/ localization link to BRENDA