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Literature summary for 7.3.2.7 extracted from

  • Pillai, J.K.; Venkadesh, S.; Ajees, A.A.; Rosen, B.P.; Bhattacharjee, H.
    Mutations in the ArsA ATPase that restore interaction with the ArsD metallochaperone (2014), Biometals, 27, 1263-1275.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 7.3.2.7

Activating Compound

Activating Compound Comment Organism Structure
ArsD a metallochaperone Escherichia coli

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Escherichia coli

Protein Variants

Protein Variants Comment Organism
D137V inactive Escherichia coli
F120I inactive Escherichia coli
Q56R the mutant exhibits significant metalloid-stimulated ATPase activity in vitro Escherichia coli

Metals/Ions

Metals/Ions Comment Organism Structure
As3+ 5.5-fold stimulation of ATPase activity at 0.1 mM Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + arsenite/in Escherichia coli
-
 ADP + phosphate + arsenite/out
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + arsenite/in
-
 Escherichia coli ADP + phosphate + arsenite/out
-
 ?

Synonyms

Synonyms Comment Organism
ArsA ATPase catalytic subunit of the ArsAB As(III) efflux pump Escherichia coli