Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(S)-methylmalonyl-CoA | substrate inhibition above 0.014 mM | Veillonella parvula | |
Avidin | - |
Veillonella parvula | |
butyryl-CoA | - |
Veillonella parvula | |
CoA | - |
Veillonella parvula | |
glutaryl-CoA | - |
Veillonella parvula | |
malonyl-CoA | - |
Veillonella parvula | |
PCMB | - |
Veillonella parvula | |
succinyl-CoA | - |
Veillonella parvula |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.002 | - |
(S)-methylmalonyl-CoA | - |
Veillonella parvula |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
275000 | 300000 | sucrose density gradient centrifugation | Veillonella parvula |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-methylmalonyl-CoA + Na+[side 1] + H+[side 2] | Veillonella parvula | the enzyme is responsible for the formation of the propionate moiety in the fermentation of lactate and the decarboxylation of succinate | propanoyl-CoA + CO2 + Na+[side 2] | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Veillonella parvula | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial | Veillonella parvula |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-methylmalonyl-CoA + Na+[side 1] + H+[side 2] | irreversible | Veillonella parvula | propanoyl-CoA + CO2 + Na+[side 2] | - |
? | |
(S)-methylmalonyl-CoA + Na+[side 1] + H+[side 2] | the enzyme is responsible for the formation of the propionate moiety in the fermentation of lactate and the decarboxylation of succinate | Veillonella parvula | propanoyl-CoA + CO2 + Na+[side 2] | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5.5 | 7 | - |
Veillonella parvula |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
biotin | prosthetic group | Veillonella parvula |