Cloned (Comment) | Organism |
---|---|
OSA1 expression analysis, and phylogenetic analysis, overview. No complementation of Saccharomyces cerevisiae mutant strain W303-1A abc1THIS3 by the wild-type enzyme | Arabidopsis thaliana |
Protein Variants | Comment | Organism |
---|---|---|
additional information | despite sharing homology to the mitochondrial ABC1 of Saccharomyces cerevisiae, Arabidopsius thaliana OSA1 is not able to complement yeast strains deleted in the endogenous ABC1 gene. The atosa1-1 and atosa1-2 T-DNA insertion mutants are more affected than wild-type plants by Cd2+ and reveal an increased sensitivity toward oxidative stress caused by hydrogen peroxide and highlight. The mutants exhibit higher superoxide dismutase activities and differences in the expression of genes involved in the antioxidant pathway, phernotype, overview | Arabidopsis thaliana |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
chloroplast | envelope membrane | Arabidopsis thaliana | 9507 | - |
membrane | - |
Arabidopsis thaliana | 16020 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
70000 | - |
x * 70000 | Arabidopsis thaliana |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + Cd2+/in | Arabidopsis thaliana | chloroplast envelope membrane protein OSA1, a member of the Abc1-like family, acts as a factor in cadmium and oxidative stress response, playing a role in the balance of oxidative stress | ADP + phosphate + Cd2+/out | - |
? | |
additional information | Arabidopsis thaliana | in the absence of Cd21, an increase in the expression of AtOSA1 is correlated with plant aging. The transcript level of AtOSA1, which is age dependent, is also down-regulated in the night, circadian rhythm dependencies, and senescent leaves | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | Q0WLU3 | ecotype Col-0 | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | - |
Arabidopsis thaliana |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
flower | - |
Arabidopsis thaliana | - |
leaf | high expression level | Arabidopsis thaliana | - |
additional information | poor expression in roots | Arabidopsis thaliana | - |
stem | low expression level | Arabidopsis thaliana | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + Cd2+/in | - |
Arabidopsis thaliana | ADP + phosphate + Cd2+/out | - |
? | |
ATP + H2O + Cd2+/in | chloroplast envelope membrane protein OSA1, a member of the Abc1-like family, acts as a factor in cadmium and oxidative stress response, playing a role in the balance of oxidative stress | Arabidopsis thaliana | ADP + phosphate + Cd2+/out | - |
? | |
additional information | in the absence of Cd21, an increase in the expression of AtOSA1 is correlated with plant aging. The transcript level of AtOSA1, which is age dependent, is also down-regulated in the night, circadian rhythm dependencies, and senescent leaves | Arabidopsis thaliana | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 70000 | Arabidopsis thaliana |
Synonyms | Comment | Organism |
---|---|---|
More | the enzyme is a member of the Abc1-like family | Arabidopsis thaliana |
OSA1 | - |
Arabidopsis thaliana |
oxidative stress-related Abc1-like protein | - |
Arabidopsis thaliana |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Arabidopsis thaliana |