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Information on EC 7.2.2.2 - ABC-type Cd2+ transporter

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IUBMB Comments
An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. Does not undergo phosphorylation during the transport process. A yeast enzyme that exports some heavy metals, especially Cd2+, from the cytosol into the vacuole.
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
ATP phosphohydrolase (heavy-metal-exporting), cadmium-transporting ATPase, cadmium-transporting P1B-type ATPase, CzcP, half-molecule ATP-binding cassette (ABC) transporter, heavy metal tolerance factor 1, heavy metal-associated ATPase, HMA3, HMT-1, HMT1 protein, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + H2O + Cd2+[side 1] = ADP + phosphate + Cd2+[side 2]
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ABC-type (ATP-binding cassette) ATPase, characterized by the presence of two similar ATP-binding domains. Does not undergo phosphorylation during the transport process. A yeast enzyme that exports some heavy metals, especially Cd2+, from the cytosol into the vacuole.
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