Literature summary for 7.2.2.10 extracted from

Marechal, X.; De Mendonca, R.; Miras, R.; Revilloud, J.; Catty, P.
Functional characterization of the Ca2+-ATPase SMA1 from Schistosoma mansoni (2018), Biochem. J., 475, 289-303 .

Search for more literature for 7.2.2.10

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Saccharomyces cerevisiae strain YPH 500	Schistosoma mansoni

Protein Variants

Protein Variants	Comment	Organism
D354A	the mutant enzyme is not getting phosphorylated	Schistosoma mansoni

Inhibitors

Inhibitors	Comment	Organism	Structure
cyclopiazonic acid	-	Schistosoma mansoni
thapsigargin	-	Schistosoma mansoni

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + H2O + Ca2+[side 1]	Schistosoma mansoni	-	ADP + phosphate + Ca2+[side 2]	-	?

Organism

Organism	UniProt	Comment	Textmining
Schistosoma mansoni	-	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
phosphoprotein	-	Schistosoma mansoni

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + H2O + Ca2+[side 1]	-	Schistosoma mansoni	ADP + phosphate + Ca2+[side 2]	-	?

Subunits

Subunits	Comment	Organism
?	x * 112594, calculated from amino acid sequence	Schistosoma mansoni

Synonyms

Synonyms	Comment	Organism
Ca2+-ATPase	-	Schistosoma mansoni
SMA1	-	Schistosoma mansoni

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.0263	-	thapsigargin	at pH 7.0 and 25°C	Schistosoma mansoni

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Release 2023.1 (January 2023)