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Literature summary for 7.2.2.10 extracted from

  • Kjelstrup, S.; de Meis, L.; Bedeaux, D.; Simon, J.M.
    Is the Ca2+-ATPase from sarcoplasmic reticulum also a heat pump? (2008), Eur. Biophys. J., 38, 59-67.
    View publication on PubMed
Search for more literature for 7.2.2.10

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
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 Oryctolagus cuniculus 5783
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sarcoplasmic reticulum
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 Oryctolagus cuniculus 16529
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Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ dependent on, there are two binding sites for Ca2+ Oryctolagus cuniculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Oryctolagus cuniculus SERCA 2 type Ca2+-ATPases dominate in red muscle and blood platelets where this heat flux is not so central ?
-
 ?
additional information Oryctolagus cuniculus the SERCA 1 Ca2+-ATPase in white muscle is able to work as ion pumps, but clearly also as heat pumps because of their large ATPase activity. This may explain why SERCA 1 type Ca2+-ATPases dominate in tissues where thermal regulation is important. ?
-
 ?

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
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-
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Oryctolagus cuniculus P04191
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Oryctolagus cuniculus P20647
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood platelet isoform SERCA 2 Oryctolagus cuniculus
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blood platelet isoform SERCA 3 Oryctolagus cuniculus
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fast twitch muscle fiber isoform SERCA 1 Oryctolagus cuniculus
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slow twitch muscle fiber isoform SERCA 2 Oryctolagus cuniculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Ca2+/cis
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 Oryctolagus cuniculus ADP + phosphate + Ca2+/trans
-
 ?
additional information SERCA 2 type Ca2+-ATPases dominate in red muscle and blood platelets where this heat flux is not so central Oryctolagus cuniculus ?
-
 ?
additional information the SERCA 1 Ca2+-ATPase in white muscle is able to work as ion pumps, but clearly also as heat pumps because of their large ATPase activity. This may explain why SERCA 1 type Ca2+-ATPases dominate in tissues where thermal regulation is important. Oryctolagus cuniculus ?
-
 ?

Synonyms

Synonyms Comment Organism
Ca2+-ATPase
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 Oryctolagus cuniculus
SERCA 1 isoform Oryctolagus cuniculus
SERCA 2 isoform Oryctolagus cuniculus
SERCA 3 isoform Oryctolagus cuniculus