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Literature summary for 7.2.2.10 extracted from

  • Mandal, P.K.; Mandal, A.; Ahearn, G.A.
    Physiological characterization of 45Ca2+ and 65Zn2+ transport by lobster hepatopancreatic endoplasmic reticulum (2005), J. Exp. Zool. A, 303, 515-526.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Cu2+ reduces the Ca2+ content in the cytosol Homarus sp.
thapsigargin
-
Homarus sp.
vanadate
-
Homarus sp.
Zn2+ reduces the Ca2+ content in the cytosol Homarus sp.

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
additional information kinetics Homarus sp.

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum membrane
-
Homarus sp. 5789
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + Ca2+/cis Homarus sp.
-
ADP + phosphate + Ca2+/trans
-
?
additional information Homarus sp. the enzyme is involved in the transepithelial Ca2+ flow in hepatopancreas of lobster acting as an ATP-driven Ca2+ pump in conjunction with a Na+/Ca2+ antiporter in the basolateral cell region, Ca2+ transport mechanism by endoplasmic reticular vesicles, overview ?
-
?

Organism

Organism UniProt Comment Textmining
Homarus sp.
-
lobster
-

Source Tissue

Source Tissue Comment Organism Textmining
hepatopancreas
-
Homarus sp.
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Ca2+/cis
-
Homarus sp. ADP + phosphate + Ca2+/trans
-
?
ATP + H2O + Ca2+/cis the enzyme performs ATP-dependent Ca2+ transport and Ca2+-dependent ATPase activity Homarus sp. ADP + phosphate + Ca2+/trans
-
?
additional information the enzyme is involved in the transepithelial Ca2+ flow in hepatopancreas of lobster acting as an ATP-driven Ca2+ pump in conjunction with a Na+/Ca2+ antiporter in the basolateral cell region, Ca2+ transport mechanism by endoplasmic reticular vesicles, overview Homarus sp. ?
-
?

Synonyms

Synonyms Comment Organism
ATP-dependent calcium ATPase
-
Homarus sp.
SERCA-like calcium ATPase
-
Homarus sp.