Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(2R)-2-[(5Z)-5-[[3-(4-fluorophenoxy)phenyl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-phenylpropanoic acid | - |
Staphylococcus aureus | |
(2S)-2-[(5Z)-4-oxo-5-[(3-phenoxyphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-phenylpropanoic acid | - |
Staphylococcus aureus | |
(2S)-2-[(5Z)-4-oxo-5-[(3-[[(2Z)-3-phenylprop-2-en-1-yl]oxy]phenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-phenylpropanoic acid | - |
Staphylococcus aureus | |
(2S)-2-[(5Z)-5-([3-[(3,4-dichlorophenyl)methyl]phenyl]methylidene)-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-phenylpropanoic acid | - |
Staphylococcus aureus | |
(2S)-2-[(5Z)-5-[(3',4'-dichloro[1,1'-biphenyl]-3-yl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-phenylpropanoic acid | - |
Staphylococcus aureus | |
(2S)-2-[(5Z)-5-[(3-benzoylphenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-phenylpropanoic acid | - |
Staphylococcus aureus | |
(2S)-2-[(5Z)-5-[(3-benzylphenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-phenylpropanoic acid | - |
Staphylococcus aureus | |
(2S)-2-[(5Z)-5-[([1,1'-biphenyl]-3-yl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-phenylpropanoic acid | - |
Staphylococcus aureus | |
(2S)-2-[(5Z)-5-[[3-(3,4-dichlorophenoxy)phenyl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-phenylpropanoic acid | - |
Staphylococcus aureus | |
(2S)-2-[(5Z)-5-[[3-(3-chlorophenoxy)phenyl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-phenylpropanoic acid | - |
Staphylococcus aureus | |
(2S)-2-[(5Z)-5-[[3-(benzyloxy)phenyl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-phenylpropanoic acid | - |
Staphylococcus aureus | |
novobiocin | - |
Staphylococcus aureus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required for activity | Staphylococcus aureus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Staphylococcus aureus | - |
- |
- |
Staphylococcus aureus | P0A0K8 | subunit B | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + relaxed pBR322 DNA | - |
Staphylococcus aureus | ADP + phosphate + supercoiled pBR322 DNA | - |
? | |
ATP + supercoiled pBR322 DNA | - |
Staphylococcus aureus | ADP + phosphate + relaxed pBR322 DNA | - |
? |
Subunits | Comment | Organism |
---|---|---|
heterodimer | - |
Staphylococcus aureus |
Synonyms | Comment | Organism |
---|---|---|
DNA gyrase | - |
Staphylococcus aureus |
topoisomerase IV | - |
Staphylococcus aureus |
topoIV | - |
Staphylococcus aureus |
type IIA topoisomerase | - |
Staphylococcus aureus |