Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | geldanamycin does not inhibit the decatenation and relaxation activities | Saccharolobus shibatae | |
radicicol | inhibits the decatenation and relaxation activities | Saccharolobus shibatae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharolobus shibatae | O05207 and O05208 | O05207: subunit B, O05208: subunit A | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
catenated DNA + ATP + H2O | decatenation | Saccharolobus shibatae | minicircular DNA + ADP + phosphate | - |
? | |
relaxed pBR322 plasmid + ATP + H2O | supercoiling | Saccharolobus shibatae | supercoiled pBR322 plasmid + ADP + phosphate | - |
? | |
supercoiled pBR322 plasmid + ATP + H2O | relaxation | Saccharolobus shibatae | relaxed pBR322 plasmid + ADP + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DNA topoisomerase VI | - |
Saccharolobus shibatae |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
74 | - |
assay at | Saccharolobus shibatae |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Saccharolobus shibatae |