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Literature summary for 5.6.2.2 extracted from
- Lim15/Dmc1 enhances DNA topoisomerase II catenation activity independent of sequence homology (2008), Chromosoma, 117, 297-302.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Lim15 | enhances DNA topoisomerase II catenation activity, the percentage of reaction products is about 3fold higher in the presence of 0.00192 mM Lim15 than when 30 nM Lim15 is used | Coprinopsis cinerea |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| histidine-tagged full-length TopII protein is expressed using the BAC-TOBAC HT baculovirus expression system | Coprinopsis cinerea |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Coprinopsis cinerea | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Coprinopsis cinerea |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| supercoiled DNA + ATP + H2O | - |
Coprinopsis cinerea | catenated DNA networks + ADP + phosphate | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| DNA topoisomerase II | - |
Coprinopsis cinerea |
| TopII | - |
Coprinopsis cinerea |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Coprinopsis cinerea | |
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Release 2023.1 (January 2023)
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