Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Berenil | - |
Trypanosoma cruzi | |
Clorobiocin | - |
Trypanosoma cruzi | |
coumermycin | coumermycin A2 | Trypanosoma cruzi | |
ellipticines | - |
Trypanosoma cruzi | |
Hydroxystilbamidine | - |
Trypanosoma cruzi | |
KCl | above 50 mM | Trypanosoma cruzi | |
NaCl | above 50 mM | Trypanosoma cruzi |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | can substitute for Mg2+ | Trypanosoma cruzi | |
K+ | required | Trypanosoma cruzi | |
Mg2+ | required | Trypanosoma cruzi | |
Mn2+ | can substitute for Mg2+ | Trypanosoma cruzi |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
200000 | - |
sedimentation equilibrium centrifugation | Trypanosoma cruzi |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma cruzi | - |
- |
- |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Trypanosoma cruzi |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme can alter the linking number of DNA only in steps of two | Trypanosoma cruzi | ? | - |
? | |
additional information | unknotting activity | Trypanosoma cruzi | ? | - |
? | |
additional information | no ATPase activity | Trypanosoma cruzi | ? | - |
? | |
network of DNA rings + ATP + H2O | decatenation | Trypanosoma cruzi | monomeric DNA circles + ADP + phosphate | - |
? | |
supercoiled DNA + ATP + H2O | catenation | Trypanosoma cruzi | catenated DNA networks + ADP + phosphate | - |
? | |
supercoiled DNA + ATP + H2O | catenation in absence of ATP | Trypanosoma cruzi | catenated DNA networks + ADP + phosphate | - |
? | |
supercoiled DNA + ATP + H2O | relaxation | Trypanosoma cruzi | relaxed DNA + ADP + phosphate | - |
? |