Literature summary for 5.6.2.2 extracted from

Frere-Gallois, V.; Krebs, D.; Scala, D.; Troalen, F.; Fermandjian, S.
Peptide fragments of DNA topoisomerase II with helix-forming and coiled-coil-forming properties act as inhibitors of the enzyme (1979), Eur. J. Biochem., 249, 142-148.

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Inhibitors

Inhibitors	Comment	Organism	Structure
Peptide fragments of DNA topoisomerase II with helix-forming and coiled-coil-forming properties	-	Saccharomyces cerevisiae

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
network of DNA rings + ATP + H2O	decatenation	Saccharomyces cerevisiae	monomeric DNA circles + ADP + phosphate	-	?
supercoiled DNA + ATP + H2O	catenation	Saccharomyces cerevisiae	catenated DNA networks + ADP + phosphate	-	?
supercoiled DNA + ATP + H2O	relaxation	Saccharomyces cerevisiae	relaxed DNA + ADP + phosphate	-	?

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Release 2023.1 (January 2023)