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Literature summary for 5.3.99.3 extracted from

  • Lin, Y.M.; Fu, Y.; Hegde, S.; Tang, Y.; Radhakrishnan, R.; Shi, X.Z.
    Microsomal prostaglandin E synthase-1 plays a critical role in long-term motility dysfunction after bowel obstruction (2018), Sci. Rep., 8, 8831 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.3.99.3

Inhibitors

Inhibitors Comment Organism Structure
Cay 10526
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Rattus norvegicus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Prostaglandin H2 Rattus norvegicus
-
 Prostaglandin E2
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
colon
-
 Rattus norvegicus
-
gut
-
 Rattus norvegicus
-
smooth muscle cell
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Prostaglandin H2
-
 Rattus norvegicus Prostaglandin E2
-
 ?

Synonyms

Synonyms Comment Organism
microsomal prostaglandin E synthase-1
-
 Rattus norvegicus
mPGES
-
 Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus the enzyme expression increases in the distended bowel during obstruction up

General Information

General Information Comment Organism
physiological function the enzyme plays a critical role in the continuous suppression of motor function in the post-bowel obstruction state Rattus norvegicus