Activating Compound | Comment | Organism | Structure |
---|---|---|---|
GSH | the enzyme activity is increased in the presence of reduced glutathione | Gammarus sp. KV-2010a | |
GSH | the enzyme activity is increased in the presence of reduced glutathione | Caprella sp. KV-2010a |
Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21(DE3)RP cells | Gammarus sp. KV-2010a |
expressed in Escherichia coli BL21(DE3)RP cells | Caprella sp. KV-2010a |
General Stability | Organism |
---|---|
the enzyme stability is increased in the presence of reduced glutathione | Gammarus sp. KV-2010a |
the enzyme stability is increased in the presence of reduced glutathione | Caprella sp. KV-2010a |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-hydroxymercuribenzoate | - |
Caprella sp. KV-2010a | |
4-hydroxymercuribenzoate | - |
Gammarus sp. KV-2010a |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Gammarus sp. KV-2010a | 16020 | - |
membrane | - |
Caprella sp. KV-2010a | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Prostaglandin H2 | Gammarus sp. KV-2010a | - |
Prostaglandin E2 | - |
? | |
Prostaglandin H2 | Caprella sp. KV-2010a | - |
Prostaglandin E2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Caprella sp. KV-2010a | S4VIU3 | - |
- |
Gammarus sp. KV-2010a | S4VLK7 | - |
- |
Purification (Comment) | Organism |
---|---|
Ni-NTA column chromatography, and Superdex 200 gel filtration | Gammarus sp. KV-2010a |
Ni-NTA column chromatography, and Superdex 200 gel filtration | Caprella sp. KV-2010a |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Prostaglandin H2 | - |
Gammarus sp. KV-2010a | Prostaglandin E2 | - |
? | |
Prostaglandin H2 | - |
Caprella sp. KV-2010a | Prostaglandin E2 | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 39000, N-terminally truncated His6-tagged enzyme, SDS-PAGE | Gammarus sp. KV-2010a |
? | x * 39000, N-terminally truncated His6-tagged enzyme, SDS-PAGE | Caprella sp. KV-2010a |
Synonyms | Comment | Organism |
---|---|---|
PGE synthase | - |
Gammarus sp. KV-2010a |
PGE synthase | - |
Caprella sp. KV-2010a |
PGES-2 | - |
Gammarus sp. KV-2010a |
PGES-2 | - |
Caprella sp. KV-2010a |
prostaglandin E synthase-2 | - |
Gammarus sp. KV-2010a |
prostaglandin E synthase-2 | - |
Caprella sp. KV-2010a |