Application | Comment | Organism |
---|---|---|
additional information | H2S might be a novel insulin resistance regulator | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Beta-cyano-L-alanine | pretreating adiopose tissues with the CSE inhibitor beta-cyano-L-alanine (BCA) (2 mmol/l) for 20 min significantly decreased the endogenous H2S production by 89%, as compared with controls | Rattus norvegicus | |
DL-propargylglycine | pretreating adiopose tissues with the CSE inhibitor DL-propargylglycine (PPG) (10 mmol/l) for 20 min significantly decreased the endogenous H2S production by 85%, as compared with controls | Rattus norvegicus | |
additional information | administration of CSE inhibitors enhances the glucose uptake of adipocytes | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
43000 | - |
Western blot analysis, SDS-PAGE | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
76 male Sprague-Dawley rats (200-250 g), 96 different age rats (from 1 month to 12 months old) and insulin-resistant animals | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adipocyte | - |
Rattus norvegicus | - |
kidney | - |
Rattus norvegicus | - |
liver | - |
Rattus norvegicus | - |
preadipocyte | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-cysteine + H2O | - |
Rattus norvegicus | sulfide + NH3 + pyruvate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CSE | - |
Rattus norvegicus |
cystathionine gamma lyase | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Rattus norvegicus |