Literature summary for 3.9.1.3 extracted from

Martin, D.R.; Dutta, P.; Mahajan, S.; Varma, S.; Stevens, S.M.
Structural and activity characterization of human PHPT1 after oxidative modification (2016), Sci. Rep., 6, 23658 .

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Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q9NRX4	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
[peptide]-N-phospho-L-histidine + H2O	H2O2 exposure induces selective oxidation of hPHPT1 at Met95, a residue within the substrate binding region. H2O2-induced oxidation does not impact hPHPT1 function negatively	Homo sapiens	[peptide]-L-histidine + phosphate	-	?

Synonyms

Synonyms	Comment	Organism
phosphohistidine phosphatase 1	-	Homo sapiens
PHPT1	-	Homo sapiens

General Information

General Information	Comment	Organism
additional information	H2O2 exposure induces selective oxidation of hPHPT1 at Met95, a residue within the substrate binding region. H2O2-induced oxidation does not impact hPHPT1 function negatively	Homo sapiens

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Release 2023.1 (January 2023)