Literature summary for 3.9.1.3 extracted from

Xu, A.; Li, X.; Li, S.; Sun, L.; Wu, S.; Zhang, B.; Huang, J.
A novel role for 14-kDa phosphohistidine phosphatase in lamellipodia formation (2017), Cell Adh. Migr., 11, 488-495 .

Search for more literature for 3.9.1.3

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q9NRX4	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
HeLa cell	colocalization of the enzyme (PHP14) with Arp3 and F-actin at the leading edge of migrating cells. PHP14 is recruited to the actin remodeling sites in parallel with Arp3 during lamellipodia formation	Homo sapiens	-
LX-2 cell	colocalization of the enzyme (PHP14) with Arp3 and F-actin at the leading edge of migrating cells. PHP14 is recruited to the actin remodeling sites in parallel with Arp3 during lamellipodia formation	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
PHP14	-	Homo sapiens

General Information

General Information	Comment	Organism
malfunction	PHP14 knockdown impairs Arp3 localization at the leading edge of lamellipodia, as well as lamellipodia formation	Homo sapiens
physiological function	role for PHP14 in the dynamic regulation of the actin cytoskeleton and cell migration	Homo sapiens

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Release 2023.1 (January 2023)