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Literature summary for 3.4.22.43 extracted from

  • Zeeuwen, P.L.; Cheng, T.; Schalkwijk, J.
    The biology of cystatin M/E and its cognate target proteases (2009), J. Invest. Dermatol., 129, 1327-1338.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
cystatin M/E high-affinity inhibitor of cathepsin V, directly controls the activity of cathepsin V Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
epidermis
-
Homo sapiens
-
hair follicle in the root sheath of the hair follicles Homo sapiens
-
stratum granulosum
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
CTSL2
-
Homo sapiens
CTSV
-
Homo sapiens
stratum corneum thiol protease
-
Homo sapiens

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.00000047
-
cystatin M/E pH and temperature not specified in the publication Homo sapiens

General Information

General Information Comment Organism
physiological function CTSV is involved in the breakdown of corneodesmosomal proteins Homo sapiens