Cloned (Comment) | Organism |
---|---|
expressed in Pichia pastoris | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
plasminogen + H2O | Homo sapiens | cathepsin V hydrolyzes plasminogen at Phe94-Glu95, Ser358-Thr359, and Val468-Leu469 generating angiostatin-related fragments | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HUVEC cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-aminobenzoyl-KPPVVLLPDQ-N-[2,4-dinitrophenyl]ethylenediamine + H2O | - |
Homo sapiens | 2-aminobenzoyl-KPPVV + LLPDQ-N-[2,4-dinitrophenyl]ethylenediamine | - |
? | |
2-aminobenzoyl-KPVSTEQLAQ-N-[2,4-dinitrophenyl]ethylenediamine + H2O | - |
Homo sapiens | 2-aminobenzoyl-KPVS + TEQLAQ-N-[2,4-dinitrophenyl]ethylenediamine | - |
? | |
2-aminobenzoyl-LFEKQ-N-[2,4-dinitrophenyl]ethylenediamine + H2O | - |
Homo sapiens | 2-aminobenzoyl-LF + EKQ-N-[2,4-dinitrophenyl]ethylenediamine | - |
? | |
2-aminobenzoyl-VLFEKKQ-N-[2,4-dinitrophenyl]ethylenediamine + H2O | selective substrate for cathepsin V when compared with cathepsins B, L, and S | Homo sapiens | 2-aminobenzoyl-VLF + EKKQ-N-[2,4-dinitrophenyl]ethylenediamine | - |
? | |
2-aminobenzoyl-VLFEKKVYLQ-N-[2,4-dinitrophenyl]ethylenediamine + H2O | - |
Homo sapiens | 2-aminobenzoyl-VLF + EKKVY + LQ-N-[2,4-dinitrophenyl]ethylenediamine | - |
? | |
2-aminobenzoyl-VLFEKQ-N-[2,4-dinitrophenyl]ethylenediamine + H2O | - |
Homo sapiens | 2-aminobenzoyl-VLF + EKQ-N-[2,4-dinitrophenyl]ethylenediamine | - |
? | |
plasminogen + H2O | cathepsin V hydrolyzes plasminogen at Phe94-Glu95, Ser358-Thr359, and Val468-Leu469 generating angiostatin-related fragments | Homo sapiens | ? | - |
? |
kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
496 | - |
2-aminobenzoyl-KPPVVLLPDQ-N-[2,4-dinitrophenyl]ethylenediamine | at 37°C, in 0.1 M sodium acetate buffer, pH 5.5 | Homo sapiens | |
903 | - |
2-aminobenzoyl-KPVSTEQLAQ-N-[2,4-dinitrophenyl]ethylenediamine | at 37°C, in 0.1 M sodium acetate buffer, pH 5.5 | Homo sapiens | |
3055 | - |
2-aminobenzoyl-VLFEKKQ-N-[2,4-dinitrophenyl]ethylenediamine | at 37°C, in 0.1 M sodium acetate buffer, pH 5.5 | Homo sapiens | |
4277 | - |
2-aminobenzoyl-VLFEKQ-N-[2,4-dinitrophenyl]ethylenediamine | at 37°C, in 0.1 M sodium acetate buffer, pH 5.5 | Homo sapiens | |
4528 | - |
2-aminobenzoyl-LFEKQ-N-[2,4-dinitrophenyl]ethylenediamine | at 37°C, in 0.1 M sodium acetate buffer, pH 5.5 | Homo sapiens | |
6833 | - |
2-aminobenzoyl-VLFEKKVYLQ-N-[2,4-dinitrophenyl]ethylenediamine | at 37°C, pH 5.5 | Homo sapiens |