Activating Compound | Comment | Organism | Structure |
---|---|---|---|
atorvastatin | significantly increases circulating PCSK9 levels by 34% compared with baseline and placebo and decreases low density lipoprotein cholesterol levels by 42% | Homo sapiens |
Application | Comment | Organism |
---|---|---|
medicine | PCSK9 is an attractive drug target for decreasing low density lipoprotein cholesterol levels. Addition of a PCSK9 inhibitor to statin therapy may result in even further low density lipoprotein cholesterol level decreases | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
serum | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
PCSK9 | - |
Homo sapiens |
proprotein convertase subtilisin/kexin type 9 | - |
Homo sapiens |