Literature summary for 3.4.21.46 extracted from

Li, L.; Liu, B.; Li, X.; Yang, S.; Xiao, J.; Chen, M.; Zhang, Y.; Ma, J.
Vascular endothelial growth factor D and intratumoral lymphatics as independent prognostic factors in epithelial ovarian carcinoma (2009), Anat. Rec. (Hoboken), 292, 562-569.

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Application

Application	Comment	Organism
medicine	VEGF-D plays an essential role in tumoral lymphangiogenesis and lymphatic spread, VEGF-D expression, and the intratumoral lymphatics may be clinically useful indicators for prognostic evaluation in patients with epithelial ovarian carcinoma	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytoplasm	is mainly expressed in the cytoplasm of tumor cells	Homo sapiens	5737	-
additional information	occasionally in peritumoral stroma	Homo sapiens	-	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	O43915	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
additional information	epithelial ovarian carcinoma and tumoral lymphatic vessels, high expression of VEGF-D is closely associated with the FIGO stage, intratumoral lymphatic vessels, tumoral lymphatic invasion, and lymph node metastasis as well as a shorter overall survival	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
vascular endothelial growth factor D	-	Homo sapiens
VEGF-D	-	Homo sapiens

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Release 2023.1 (January 2023)